We went through 4 rounds of IVF - we knew we were ready to move on to adoption when we were sitting in the Repro/Endo's office after the 4th failed IVF round and he wanted us to try one more time and I just knew in my heart I couldn't go through it again. The roller coasters of ultra sounds every other day, counting how many eggs I'd produced, their quality, the test results etc etc....I was just tired of it all and really didn't care that I wouldn't have a biological child. We are still waiting now to adopt, and don't get me wrong, it too has a different sort of roller coasters, but at least I'm not being stuck with 5 needles a day and at some point we will have a child, if I can just be patient enough.